completely different networks

Odd plain IP routing.

completely different Nats

The Bitcoin community protocol makes use of normal TCP sockets with a typical vacation spot TCP-port variety of 8333.

The usage of Community Tackle Translation (NAT) by many last-hop routers makes it tougher to hook up with Bitcoin nodes that use IPV4 personal addresses behind a router. In idea using IPV6 addresses ought to make this subject go away.

I consider the NAT traversal for Bitcoin IPV4 TCP connections in all probability makes use of no matter options are offered by the underlying community libraries and/or are configured within the OS by the end-user.

As far as I do know, there is not a Bitcoin-specific answer for this. There are a number of basic options that could be acceptable to make use of.

See